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← FORMULARYRECORD 30S-SR-01FORMAT SERUM
NO. 01
0130 ML
PACKAGINGAMBER GLASS / AIRLESS PUMP
FILL30 ML
DOSES≈ 150
COST / DOSE£0.45
PRICE£68

SPECIMEN CATALOGUE — NO ORDER WILL BE PLACED

SERUM / AM

ASCORBIC 15%

Morning antioxidant, compounded at low pH.

HANDLING NOTE

Stings on application for 20–40 s. This is the pH doing its job.

ACTIVE LOAD18.0%
WORKING pH3.0 ± 0.2
VISCOSITY12 cP
FINISHMatte
FORMULATION
BASEAnhydrous-adjacent aqueous, propanediol carrier
TEXTUREThin, fast-absorbing, faint drag
STABILITY90 DAYS FROM OPENING — DISCARD IF AMBER
PEAK IRRITATION3 / 10
SCHEDULE
PHASEAM
STEP ORDER02
FREQUENCYDAILY
DOSE4 DROPS
01

Composition

% W/W AT COMPOUNDING
  • A-04L-Ascorbic AcidA

    Ascorbic Acid

    The only vitamin C with a real evidence base. Also the least stable molecule we handle.

    ACTS AT EPIDERMISONSET 8–12 WKIRRITATION 3/10
    CONC.15%
    83% OF ACTIVE LOAD
  • A-11PanthenolB

    Panthenol

    The quiet one. Its whole job is making the other actives survivable.

    ACTS AT STRATUM CORNEUMONSET 1 WKIRRITATION 0/10
    CONC.3%
    17% OF ACTIVE LOAD
FULL INCI, DESCENDING
  1. 01Aqua
  2. 02Ascorbic Acid
  3. 03Propanediol
  4. 04Panthenol
  5. 05Tocopherol
  6. 06Ferulic Acid
  7. 07Sodium Hyaluronate
  8. 08Glycerin
EXCLUDED BY POLICY
  • FRAGRANCE
  • DENAT. ALCOHOL
  • ESSENTIAL OILS
  • COLOURANT
02

Measured endpoints

MEDIAN CHANGE VS. VEHICLE
Global photodamage score-29%
24 WKREF-10
Melanin index (MASI)-24%
16 WKREF-04
SUPPORTING RECORDS
  • REF-04A

    Randomised, active-controlled

    N=96 · 16 WK · DOUBLE-BLIND

  • REF-10A

    Randomised, active-controlled

    N=144 · 24 WK · DOUBLE-BLIND

  • REF-12C

    In vitro enzymatic assay

    N=12 · N/A · N/A

RECORDS ARE ILLUSTRATIVE PLACEHOLDERS AUTHORED FOR THIS SPECIMEN CATALOGUE. THEY CITE NO REAL STUDY, AUTHOR OR JOURNAL.
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