The
ledger
Guides to prescription skincare companies, treatment options and costs, alongside house notes on dose, methods and disclosure.
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Curology vs Agency: compare the current prescription, price and treatment goal
Curology's acne offer and Agency's renamed aging range are different starting points. A useful comparison records the proposed formula and actual bill before deciding whether either service fits.
Archive
- L-172026-09-13
Adult acne prescription combinations: what the ingredients change
A fixed combination, a custom formula and separate prescriptions create different tradeoffs. Compare the antibiotic, retinoid, vehicle and follow-up plan before counting how many actives fit in a pump.
ADULT ACNEANTIBIOTICSRETINOIDS2 MIN - L-182026-09-13
Prescription skincare follow-up: what to establish before the first refill
A visit, a messaging window, a refill authorization and a recurring shipment are different things. Put them on one timeline before comparing services or deciding that care is included.
TELEHEALTHFOLLOW-UPPRESCRIPTIONS2 MIN - L-192026-09-13
Prescription skincare expiry and storage: compare usable treatment time
A larger pump can still have a short usable window. CABTREO and TWYNEO illustrate why the dispensing date, opening date and storage instructions belong beside the price and grams.
COSTSTORAGEPRESCRIPTIONS2 MIN - L-152026-09-13
Online prescription skincare companies: compare the route to care
Compare clinical visits, membership services, custom prescriptions and clinician-initiated compounding. The expanded directory connects company terms to the exact product, follow-up and cost questions that come next.
COMPANIESPRESCRIPTIONSCOMPARISON4 MIN - L-142026-09-13
Tretinoin online: a pharmacy prescription or a custom subscription?
The decision involves more than the active ingredient. Compare the exact medicine, clinical access, dispensing freedom and recurring terms before deciding how to obtain tretinoin.
TRETINOINCOMPOUNDINGCOMPARISON3 MIN - L-132026-10-15
What prescription skincare really costs: count the visit and the refill
A monthly headline, a consultation fee and an insured copay are different units. Build a comparable total before deciding which service costs less.
COSTSUBSCRIPTIONSDISCLOSURE6 MIN - L-122026-09-13
Rosacea prescriptions: persistent redness and bumps are different targets
A service offering rosacea cream may be describing several possible treatments. Understand the symptom being treated before comparing an ingredient list or a compounded combination.
ROSACEACOMPOUNDINGTREATMENT TARGETS3 MIN - L-112026-09-13
Before a compounded melasma prescription: five questions to ask
Diagnosis, exact ingredients, treatment area, duration and follow-up belong in the plan. A four-ingredient sales page cannot supply them for every patient.
MELASMAHYDROQUINONECOMPOUNDING3 MIN - L-102026-08-02
Proven in whom
Across seventeen registration programmes now in the register, three publish a mean or average age above thirty — and two of them are for diseases of midlife. Almost everything a forty-year-old is prescribed for their skin was measured in teenagers.
EVIDENCETRIALSREGISTER8 MIN - L-092026-09-13
The vehicle is a dose
One molecule, four approved vehicles, and irritation rates that differ by more than the concentrations do. A percentage without a base is not a specification.
FORMULATIONRETINOIDSREGISTER4 MIN - L-082026-09-13
Ask what the vehicle arm did
In sixteen controlled trials now in this register, between 3% and 58% of people improved on the base cream or the placebo tablet alone. Not one compounded product sold direct to consumers has ever published that number, because not one has ever measured it.
EVIDENCECONTROLSREGISTER5 MIN - L-072026-07-28
Where the warning lives
Across thirty-three reviews the safety copy is almost always written, and almost never on the page taking the money. Placement is now the finding, not absence.
DISCLOSUREPLACEMENTREGISTER6 MIN - L-062026-09-13
A course is not a subscription
Hydroquinone, topical steroids and oral antibiotics all require a stop. A subscription's default behaviour is that it continues. One company in the register has built the stop into the product.
DURATIONMODELREGISTER3 MIN - L-052026-07-26
Compounded is not approved
Most of the prescription skincare sold online is compounded, which means it has never been through FDA review. Four companies in this register give four different answers to that fact, and one of them gives the wrong one.
REGULATIONDISCLOSUREREGISTER6 MIN - L-042026-07-02
The number nobody publishes
Every sunscreen on earth is tested at 2 mg/cm². Almost nobody applies 2 mg/cm². The gap is the whole product.
SPFDOSEMETHOD6 MIN - L-032026-05-19
Against the actives arms race
Ten percent niacinamide is not twice as good as five. The dose–response curve flattens and the complaint rate does not.
DOSE-RESPONSEFORMULATION5 MIN - L-022026-03-08
Retinisation is not a result
The flaking at week three tells you a retinoid is present. It tells you nothing about whether it is working.
RETINOIDTOLERANCE4 MIN - L-012026-01-14
What thirty actually changes
Not a cliff. A set of slopes that were already running, becoming visible at the same time.
AGEINGMODEL7 MIN - L-202026-10-05
CoreAge, SuperHealthy and Likeness: compare the actual service
Three featured providers, different service scopes. Read the full reviews before comparing skincare formulas, monthly prices and longer-term payments.
PROVIDER COMPARISONSKINCAREBILLING6 MIN - L-70412026-10-13
A serum claim, a study result and a purchase are three different records
Seven current cosmetic reviews show why ingredient percentages, study methods, recurring prices and opened-product returns need separate checks.
COSMETICSEVIDENCEPURCHASE TERMS5 MIN - L-212026-10-22
What a Tretinoin Concentration Claim Must Demonstrate
A research register for following a concentration claim from the tested cream to a visible outcome, with separate checks for tissue measurements, uncertainty and replication.
SCIENCEMETHODSEVIDENCE13 MIN - L-222026-10-22
Retinol Evidence and the Logic of a Reliable Skin Measurement
A research register for separating a visible change, a laboratory signal and the next claim that would need testing.
SCIENCEMETHODSEVIDENCE12 MIN