Palmitoyl Tripeptide-1
Palmitoyl Tripeptide-1 + Palmitoyl Tetrapeptide-7
ALSO — MATRIX SIGNAL PEPTIDE
A forgery, essentially. We hand the fibroblast a fake breakdown signal and it rebuilds.
WHERE WE SIT IN THE PUBLISHED RANGE2% ——— 8%
4%
We compound toward the middle of the published range, not the top of it. Past the point where the dose–response curve flattens, the extra percent buys irritation and nothing else.
IDENTITY & RATINGSB
INCIPalmitoyl Tripeptide-1 + Palmitoyl Tetrapeptide-7
FAMILYSignal peptide
MOL. WEIGHT578.8 g/mol
HOUSE CONC.4% w/w
pH WINDOW5 – 6.5
ACTS ATDERMIS
DEPTH400 – 2000 µm
ONSET12–16 WK
STABILITYSTABLE
TRIALS ON FILE2
IRRITATION INDEX1 / 10
STRATUM CORNEUMEPIDERMIS▸ DERMIS
The shaded band is the depth this molecule is understood to reach. Anything below it is out of scope, whatever the label says.
01
Mechanism
EVIDENCE GRADE B
Mimics a fragment of collagen I. The fragment reads to the fibroblast as damage; the fibroblast answers by depositing new matrix. Tetrapeptide-7 suppresses interleukin-6 in parallel.
HOUSE NOTES
- Slowest active in the formulary and the one people quit first. The curve does not bend before week 12.
- No known conflicts. This is the one active you can put next to anything.
02
Layering
CONFLICTS & PAIRINGS
DO NOT LAYER
No known conflicts. This one goes next to anything in the formulary, in any order, on any night.
PAIRS WITH
03
Compounded into
1 FORMULAS