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Zinc Oxide

Zinc Oxide (non-nano)

ALSO — MINERAL FILTER

The single highest-return active in the formulary. Every other product here is repairing what this one prevents.

WHERE WE SIT IN THE PUBLISHED RANGE10% ——— 25%
22%

We compound toward the middle of the published range, not the top of it. Past the point where the dose–response curve flattens, the extra percent buys irritation and nothing else.

IDENTITY & RATINGSA
INCIZinc Oxide (non-nano)
FAMILYUV filter
MOL. WEIGHT81.38 g/mol
HOUSE CONC.22% w/w
pH WINDOW6 – 8
ACTS ATSTRATUM CORNEUM
DEPTHSURFACE
ONSETIMMEDIATE
STABILITYPHOTOSTABLE
TRIALS ON FILE2
IRRITATION INDEX0 / 10
STRATUM CORNEUMEPIDERMISDERMIS

The shaded band is the depth this molecule is understood to reach. Anything below it is out of scope, whatever the label says.

01

Mechanism

EVIDENCE GRADE A

Sits on the surface and reflects, scatters and absorbs across UVB and the full UVA range including UVA1 — the band responsible for most dermal matrix degradation.

HOUSE NOTES

  • Non-nano, so it leaves a cast. We tint it rather than shrink the particle. That is a deliberate trade.
  • 2 mg/cm² is the tested dose. Roughly a third of a teaspoon for a face and neck. Almost nobody applies this much.

MEASURED ENDPOINTS

Minimal erythema dose+58%
1 WKREF-14

SUPPORTING RECORDS

  • Controlled UV challenge

    N=40 · 1 WK · INVESTIGATOR-BLIND

02

Layering

CONFLICTS & PAIRINGS
DO NOT LAYER

No known conflicts. This one goes next to anything in the formulary, in any order, on any night.

03

Compounded into

1 FORMULAS
SPECIMEN MONOGRAPH. FIGURES AND RECORDS ARE ILLUSTRATIVE PLACEHOLDERS AND CITE NO REAL STUDY, AUTHOR OR JOURNAL. NOT MEDICAL ADVICE.
DEPTH 000%SEC