SKIP TO CONTENT
30+/SKIN
← FORMULARYRECORD 30S-SR-04FORMAT SERUM
NO. 04
0430 ML
PACKAGINGOPAQUE ALUMINIUM / AIRLESS PUMP
FILL30 ML
DOSES≈ 100
COST / DOSE£0.96
PRICE£96

SPECIMEN CATALOGUE — NO ORDER WILL BE PLACED

SERUM / PM

RETINAL 0.1%

Night resurfacing, encapsulated.

HANDLING NOTE

Begin at 3 nights per week. Retinisation peaks week 3. Do not combine with 03 on the same night.

ACTIVE LOAD5.1%
WORKING pH5.5 ± 0.2
VISCOSITY1,200 cP
FINISHSatin
FORMULATION
BASEOil-in-water emulsion, liposomal encapsulation
TEXTURELight lotion, pale yellow
STABILITY6 MONTHS FROM OPENING — AIRLESS ONLY
PEAK IRRITATION4 / 10
SCHEDULE
PHASEPM
STEP ORDER03
FREQUENCY3–7× / WEEK
DOSEPEA-SIZED
01

Composition

% W/W AT COMPOUNDING
  • A-01RetinaldehydeA

    Retinal

    The strongest retinoid available without a prescription pad. Converts faster than retinol, irritates less than tretinoin.

    ACTS AT DERMISONSET 8–12 WKIRRITATION 4/10
    CONC.0.1%
    2% OF ACTIVE LOAD
  • A-07Ceramide NPA

    Ceramide NP

    Not a moisturiser. A replacement part. Ratio matters more than concentration.

    ACTS AT STRATUM CORNEUMONSET 1–2 WKIRRITATION 0/10
    CONC.2%
    39% OF ACTIVE LOAD
  • A-11PanthenolB

    Panthenol

    The quiet one. Its whole job is making the other actives survivable.

    ACTS AT STRATUM CORNEUMONSET 1 WKIRRITATION 0/10
    CONC.3%
    59% OF ACTIVE LOAD
FULL INCI, DESCENDING
  1. 01Aqua
  2. 02Caprylic/Capric Triglyceride
  3. 03Glycerin
  4. 04Retinal
  5. 05Ceramide NP
  6. 06Cholesterol
  7. 07Panthenol
  8. 08Tocopherol
  9. 09Lecithin
EXCLUDED BY POLICY
  • FRAGRANCE
  • DENAT. ALCOHOL
  • ESSENTIAL OILS
  • JAR PACKAGING
02

Measured endpoints

MEDIAN CHANGE VS. VEHICLE
Periorbital wrinkle depth-31%
12 WKREF-01
Skin roughness (Ra)-26%
12 WKREF-13
Procollagen I expression+46%
6 WKREF-07
SUPPORTING RECORDS
  • REF-01A

    Randomised, vehicle-controlled

    N=112 · 12 WK · DOUBLE-BLIND

  • REF-07B

    Ex vivo skin explant

    N=24 · 6 WK · N/A

  • REF-13A

    Randomised, vehicle-controlled

    N=104 · 12 WK · DOUBLE-BLIND

RECORDS ARE ILLUSTRATIVE PLACEHOLDERS AUTHORED FOR THIS SPECIMEN CATALOGUE. THEY CITE NO REAL STUDY, AUTHOR OR JOURNAL.
PREVIOUS — 30S-SL-03GLYCOLIC 8%NEXT — 30S-TR-05AZELAIC 10%
DEPTH 000%SEC —