Against the actives arms race
Ten percent niacinamide is not twice as good as five. The dose–response curve flattens and the complaint rate does not.
Concentration is the easiest number to put on a bottle and the least informative one on it. It says nothing about pH, nothing about vehicle, nothing about whether the molecule reaches the layer it acts on.
A 20% vitamin C at pH 4.2 is a 0% vitamin C with a marketing budget.
We compound to the middle of the published effective range, not the top of it. Where the curve flattens, the extra percent buys irritation and nothing else — and an irritated barrier is a barrier that absorbs unpredictably, which corrupts every other step.